Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21726313 | 0.98 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPTLMNAHSD11B1 | |
| SCHEMBL31117190 | 0.97 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTLMNAHSD11B1 | |
| SCHEMBL20601546 | 0.93 | OPRM1 (0.52) | ALDH1A1SMN1; SMN2MAPTLMNAHSD11B1 | |
| SCHEMBL11047897 | 0.85 | OPRM1 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAHSD11B1 | |
| SCHEMBL31368038 | 0.85 | OPRM1 (0.51) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL23163646 | 0.84 | HRH3 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL3485457 | 0.84 | MAPT (0.54) | ALDH1A1SMN1; SMN2MAPTLMNAOPRM1 | |
| Hydrochloric Acid SCHEMBL31368108 | 0.84 | OPRM1 (0.50) | ALDH1A1SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL8568522 | 0.84 | OPRM1 (0.71) | KMT2AOPRM1CHRM3 | |
| SCHEMBL4939286 | 0.83 | HDAC4 (0.63) | ALDH1A1SMN1; SMN2MAPTLMNAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419999-B2 | Gamma lactams as prostaglandin agonists and use thereof | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2008-09-02 | — | — | US | disclosed |
| US-20050288357-A1 | Gamma lactams as prostaglandin agonists and use thereof | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288357-A1 | Gamma lactams as prostaglandin agonists and use thereof | PGF, HPGDS, PTGIS | ALDH1A1 1403/4885SMN1; SMN2 1853/4885MAPT 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.