Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6550839 | 0.82 | TRPV4 (0.38) | TRPV4ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL22140450 | 0.81 | TRPV4 (0.43) | ARTRPV4ALDH1A1HPGDKDM4E | |
| SCHEMBL5418640 | 0.79 | TRPV4 (0.59) | ARTRPV4ALDH1A1MRGPRX4PTGDR2 | |
| SCHEMBL7816047 | 0.79 | HPGD (0.51) | ALDH1A1HPGDMAPTGAATSHR | |
| SCHEMBL506595 | 0.79 | ALDH1A1 (0.42) | ARALDH1A1PTGDR2HPGDKDM4E | |
| SCHEMBL14206692 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EMAPTGAA | |
| SCHEMBL22215813 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTGAAMEN1 | |
| SCHEMBL28857557 | 0.76 | HPGD (0.40) | TRPV4ALDH1A1PTGDR2HPGDKDM4E | |
| SCHEMBL6549707 | 0.76 | VCAM1 (0.47) | TRPV4ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL25322559 | 0.76 | GAA (0.54) | ALDH1A1PTGDR2HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611166-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |