Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8951050 | 0.97 | ALOX5 (0.48) | ALOX5CYP11B1CYP11B2CYP17A1AHR | |
| SCHEMBL13741967 | 0.86 | CYP17A1 (0.52) | CYP11B1CYP11B2CYP17A1CYP1A2NOTUM | |
| SCHEMBL20003496 | 0.82 | AHR (0.52) | ALOX5AHRCYP1A2LMNACYP2A6 | |
| SCHEMBL29097690 | 0.82 | AHR (0.52) | ALOX5AHRCYP1A2LMNACYP2A6 | |
| SCHEMBL3859616 | 0.81 | ALDH1A1 (0.48) | ALOX5AHRCYP1A2MAOBBACE1 | |
| SCHEMBL13471707 | 0.81 | ALOX5 (0.43) | ALOX5AHRCYP1A2MAOBTP53 | |
| SCHEMBL19665044 | 0.81 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP17A1NOTUMMAOB | |
| SCHEMBL7766400 | 0.79 | CYP11B2 (0.48) | CYP11B1CYP11B2CYP17A1LMNACYP2A6 | |
| SCHEMBL2552043 | 0.79 | CYP11B1 (0.48) | ALOX5CYP11B1CYP11B2CYP17A1CYP1A2 | |
| SCHEMBL21728896 | 0.78 | AHR (0.48) | ALOX5AHRCYP1A2LMNACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676402-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2001-07-04 | — | — | EP | disclosed |
| US-5578244-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0676402-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |