Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17454872 | 0.78 | ALDH1A1 (0.38) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL23095180 | 0.74 | ALDH1A1 (0.49) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1636868 | 0.72 | MAPK1 (0.60) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL12345424 | 0.70 | ALDH1A1 (0.32) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL3434647 | 0.69 | ALDH1A1 (0.44) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL466198 | 0.68 | GAA (0.34) | SMN1; SMN2ALDH1A1LMNAKDM4EUSP2 | |
| SCHEMBL26085049 | 0.68 | ALDH1A1 (0.43) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL2620624 | 0.68 | CNR2 (0.42) | CNR2 | |
| SCHEMBL13652868 | 0.65 | GABBR2 (0.33) | — | |
| SCHEMBL14649773 | 0.64 | CA12 (0.47) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611158-A1 | 1,3-DI-OXO-INDENE DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS AN ANTIVIRAL, ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2020-02-19 | — | — | EP | disclosed |