SCHEMBL1073008

SCHEMBL1073008

C=C(C)C(=O)NCCCC(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
TGFBR1 P36897 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
DPP7 Q9UHL4 1/20 0.32
ACHE P22303 1/20 0.32
EPHX1 P07099 1/20 0.32
TSHR P16473 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP14 P50281 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3272669 0.89 ALDH1A1 (0.37) ALDH1A1TGFBR1GAATSHRSMN1; SMN2
SCHEMBL217295 0.83 EPHX1 (0.44) ALDH1A1TGFBR1MEN1GAAKMT2A
SCHEMBL9138395 0.81 KDM4E (0.54) ALDH1A1MEN1GAAKMT2AKDM4E
SCHEMBL28346305 0.79 KDM4E (0.37) ALDH1A1TGFBR1MEN1GAAKMT2A
SCHEMBL25557372 0.79 ANPEP (0.41) ALDH1A1TGFBR1GAAKDM4EMAPK1
SCHEMBL1197765 0.78 THRB (0.32) ALDH1A1TGFBR1GAAKMT2AEPHX1
SCHEMBL907569 0.78 KDM4E (0.52) ALDH1A1TGFBR1MEN1KMT2AKDM4E
SCHEMBL632876 0.78 KDM4E (0.46) ALDH1A1TGFBR1MEN1KMT2AKDM4E
SCHEMBL80630 0.78 ALDH1A1 (0.36) ALDH1A1MEN1GAAKMT2AEPHX1
SCHEMBL9312164 0.77 TSHR (0.42) ALDH1A1MEN1GAAKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10551345-B2 Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2020-02-04 US claimed
US-20170356877-A1 POLY AND COPOLY(N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS, LLC (US) 2017-12-14 US claimed
US-9671367-B2 Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2017-06-06 US claimed
US-20150159009-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS LLC (US) 2015-06-11 US claimed
US-20140209461-A1 Poly and Copoly(N-vinylamide)s and Their Use In Capillary Electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2014-07-31 US claimed
US-20130153421-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS, LLC (US) 2013-06-20 US claimed
EP-2053067-B1 Poly and copoly (N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS LLC (US) 2011-09-14 EP claimed
EP-2275463-A1 Support for electrophoresis containing a composition and method Life Technologies Corporation (US) 2011-01-19 EP claimed
EP-1539846-B1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS LIFE TECHNOLOGIES CORP (US) 2010-09-08 EP claimed
US-20100051461-A1 Poly and Copolyn(N-Vinylamide)s and their use in Capillary Electrophoresis Life Technologies Corporation (US) 2010-03-04 US claimed
EP-1539846-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2005-06-15 EP claimed
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides APPLIED BIOSYSTEMS, LLC 2005-02-03 US claimed
WO-2004104054-A1 POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-12-02 WO claimed
WO-2004011513-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-02-05 WO claimed
EP-0875543-B1 Single phase systeme based on coreactive copolymers ATOFINA (FR) 2003-07-02 EP claimed
EP-0875540-B1 Single phase system based on coreactive latex resins ATOFINA (FR) 2002-11-13 EP claimed
US-6107391-A MIXTURE OF TWO PARTICLE DISPERSIONS, EACH OBTAINED BY AQUEOUS EMULSION POLYMERIZATION; ONE FROM AN UNSATURATED MONOMER WITH UREA GROUPS; THE OTHER FROM AN UNSATURATED ALDEHYDE; LATEX BINDERS FOR COATINGS; STORAGE STABILITY; LOW-TEMP CROSSLINK ELF ATOCHEM S.A. (FR) 2000-08-22 US claimed
EP-0875540-A1 Single phase system based on coreactive latex resins ELF ATOCHEM S.A. (FR) 1998-11-04 EP claimed
EP-0875542-A1 Single phase system based on coreactive polymers ELF ATOCHEM S.A. (FR) 1998-11-04 EP claimed
EP-0875543-A1 Single phase systeme based on coreactive copolymers ELF ATOCHEM S.A. (FR) 1998-11-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides POLI, PCNA, POLL ALDH1A1 3357/4885TGFBR1 4144/4885MEN1 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.