Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012879 | 0.82 | GABRA1 (0.34) | POLBGAAGFERGABRA1GABRB1 | |
| SCHEMBL26674831 | 0.79 | CA1 (0.36) | ADRB2 | |
| SCHEMBL51159 | 0.77 | CA1 (0.39) | GAAADRB2 | |
| SCHEMBL21077346 | 0.73 | GABRA1 (0.48) | POLBGAAGFERGABRA1GABRB1 | |
| SCHEMBL24012440 | 0.71 | ALDH1A1 (0.35) | POLBGAAGFER | |
| SCHEMBL740098 | 0.71 | POLB (0.38) | POLBGAAGFERGABRA1GABRB1 | |
| SCHEMBL20681148 | 0.71 | LMNA (0.36) | POLBGAAGFERGABRA1GABRB1 | |
| SCHEMBL21379277 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL20223455 | 0.70 | GABRA1 (0.35) | POLBGAAGFERGABRA1ADRB2 | |
| SCHEMBL29478995 | 0.70 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035466-A1 | NOVEL SULFONEUREA COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-02-20 | — | — | WO | disclosed |