SCHEMBL84324

SCHEMBL84324

Cc1nc2cc([N+](=O)[O-])ccc2s1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.77
HTT P42858 1/20 0.77
RIPK1 Q13546 1/20 0.56
RAB9A P51151 4/20 0.53
NPC1 O15118 3/20 0.53
MAPT P10636 6/20 0.52
ALDH1A1 P00352 4/20 0.51
POLB P06746 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
ACP1 P24666 1/20 0.50
MAPK1 P28482 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
LMNA P02545 1/20 0.49
RECQL P46063 1/20 0.49
PDK1 Q15118 1/20 0.49
HSD17B10 Q99714 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3244369 0.87 SMN1; SMN2 (1.00) SMN1; SMN2HTTRIPK1RAB9ANPC1
SCHEMBL2172967 0.87 SMN1; SMN2 (0.75) SMN1; SMN2HTTRIPK1RAB9ANPC1
SCHEMBL14538999 0.84 SMN1; SMN2 (0.59) SMN1; SMN2HTTRAB9ANPC1MAPT
SCHEMBL29197494 0.82 HTT (0.56) SMN1; SMN2HTTRIPK1RAB9ANPC1
SCHEMBL30050685 0.82 HTT (0.56) SMN1; SMN2HTTRIPK1RAB9ANPC1
SCHEMBL23926457 0.81 RIPK1 (0.53) SMN1; SMN2HTTRIPK1RAB9ANPC1
SCHEMBL29361660 0.80 RIPK1 (0.52) SMN1; SMN2HTTRIPK1RAB9ANPC1
SCHEMBL2002714 0.80 RIPK1 (0.52) SMN1; SMN2HTTRIPK1RAB9ANPC1
SCHEMBL31219335 0.80 ALDH1A1 (0.77) SMN1; SMN2HTTRIPK1MAPTALDH1A1
SCHEMBL617121 0.80 RIPK1 (0.52) SMN1; SMN2HTTRIPK1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115976586-B Forward and reverse pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2025-03-14 CN claimed
CN-115976586-A Positive and negative pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2023-04-18 CN claimed
CN-115976586-B Forward and reverse pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2025-03-14 CN disclosed
CN-115976586-A Positive and negative pulse electrolytic nickel-tungsten alloy solution, preparation method, electroplating method and nickel-tungsten alloy coating 昆山一鼎工业科技有限公司 2023-04-18 CN disclosed
US-10399966-B2 Compounds for treatment of trypanosomes and neurological pathogens and uses thereof UNIVERSITY OF WASHINGTON (US) 2019-09-03 US disclosed
US-20190031649-A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2019-01-31 US disclosed
EP-2346956-B1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Henkel IP & Holding GmbH (DE) 2017-12-06 EP disclosed
EP-2346956-B1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Henkel IP & Holding GmbH (DE) 2017-12-06 EP disclosed
WO-2017127627-A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2017-07-27 WO disclosed
EP-1377640-B1 AZO COMPOUNDS AND PROCESS OF PRODUCING THE SAME AND NOVEL INTERMEDIATE COMPOUNDS USED IN THE PROCESS OF PRODUCING AZO COMPOUNDS FUJIFILM CORP (JP) 2017-05-17 EP disclosed
US-8933168-B2 Activators for two part cyanoacrylate adhesives Henkel IP & Holding GmbH (DE) 2015-01-13 US disclosed
US-20070039517-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
US-20070039517-A1 Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
US-7175268-B2 Inkjet recording ink and inkjet recording method FUJI PHOTO FILM CO., LTD. (JP) 2007-02-13 US disclosed
US-7175268-B2 Inkjet recording ink and inkjet recording method FUJI PHOTO FILM CO., LTD. (JP) 2007-02-13 US disclosed
US-20070007698-A1 Method of producting three-dimensional model FUJIFILM CORPORATION (JP) 2007-01-11 US disclosed
US-20070007698-A1 Method of producting three-dimensional model FUJIFILM CORPORATION (JP) 2007-01-11 US disclosed
EP-0116827-B1 PROCESS FOR THE PREPARATION OF BENZOTHIAZOLES BAYER AG (DE) 1991-04-10 EP disclosed
US-4808723-A Process for the preparation of benzothiazoles BAYER AKTIENGESELLSCHAFT (DE) 1989-02-28 US disclosed
EP-0116827-A2 Process for the preparation of benzothiazoles BAYER AG (DE) 1984-08-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190031649-A1 COMPOUNDS FOR TREATMENT OF TRYPANOSOMES AND NEUROLOGICAL PATHOGENS AND USES THEREOF TSPO, GBA1, NLN SMN1; SMN2 361/4885HTT 135/4885RIPK1 3345/4885
US-10399966-B2 Compounds for treatment of trypanosomes and neurological pathogens and uses thereof TSPO, GBA1, NLN SMN1; SMN2 361/4885HTT 135/4885RIPK1 3345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.