Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.74 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.74 |
| ▸ | RECQL | P46063 | 4/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.74 |
| ▸ | HTR2A | P28223 | 2/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.74 |
| ▸ | EGFR | P00533 | 2/20 | 0.74 |
| ▸ | LCK | P06239 | 1/20 | 0.74 |
| ▸ | FYN | P06241 | 1/20 | 0.74 |
| ▸ | KDM6B | O15054 | 1/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069483 | 1.00 | ALOX15 (0.74) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 | |
| SCHEMBL13661903 | 1.00 | ALOX15 (0.74) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 | |
| SCHEMBL20765409 | 1.00 | ALOX15 (0.74) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 | |
| Hydrochloric Acid SCHEMBL20765475 | 0.98 | ALOX15 (0.72) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 | |
| Hydrochloric Acid SCHEMBL20764445 | 0.98 | ALOX15 (0.72) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 | |
| Levodopa SCHEMBL27853956 | 0.86 | SLC7A5 (0.93) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 | |
| Levodopa SCHEMBL30777603 | 0.86 | SLC7A5 (0.93) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 | |
| Levodopa SCHEMBL11000382 | 0.85 | SLC7A5 (1.00) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 | |
| Levodopa SCHEMBL116907 | 0.85 | SLC7A5 (1.00) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 | |
| Levodopa SCHEMBL704089 | 0.85 | SLC7A5 (1.00) | ALOX15KDM4EHIF1AHSD17B10SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006454-B1 | NEW COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING, AND SYNTHESIS, NANO-STRUCTURE AND USE THEREOF | SHANGHAI LUMOSA THERAPEUTICS CO LTD (CN) | 2021-01-13 | — | — | EP | disclosed |
| US-20200055895-A1 | COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING | SHANGHAI LUMOSA THERAPEUTICS CO LTD (CN) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055895-A1 | COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING | SERPINC1, PLAT, F2 | ALOX15 332/4885KDM4E 3130/4885HIF1A 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.