SCHEMBL20765409

SCHEMBL20765409

NC(=O)[C@@H](N)Cc1ccc(O)c(O)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.74
KDM4E B2RXH2 6/20 0.74
HIF1A Q16665 6/20 0.74
HSD17B10 Q99714 6/20 0.74
SLC7A5 Q01650 5/20 0.74
RECQL P46063 4/20 0.74
TDP1 Q9NUW8 4/20 0.74
PTGS1 P23219 3/20 0.74
USP2 O75604 2/20 0.74
ADORA3 P0DMS8 2/20 0.74
HTR2A P28223 2/20 0.74
PTGS2 P35354 2/20 0.74
EGFR P00533 2/20 0.74
LCK P06239 1/20 0.74
FYN P06241 1/20 0.74
KDM6B O15054 1/20 0.56
PLA2G1B P04054 1/20 0.55
ALOX12 P18054 4/20 0.53
HPGD P15428 4/20 0.53
ALDH1A1 P00352 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1069483 1.00 ALOX15 (0.74) ALOX15KDM4EHIF1AHSD17B10SLC7A5
SCHEMBL21729924 1.00 ALOX15 (0.74) ALOX15KDM4EHIF1AHSD17B10SLC7A5
SCHEMBL13661903 1.00 ALOX15 (0.74) ALOX15KDM4EHIF1AHSD17B10SLC7A5
Hydrochloric Acid SCHEMBL20765475 0.98 ALOX15 (0.72) ALOX15KDM4EHIF1AHSD17B10SLC7A5
Hydrochloric Acid SCHEMBL20764445 0.98 ALOX15 (0.72) ALOX15KDM4EHIF1AHSD17B10SLC7A5
Levodopa SCHEMBL27853956 0.86 SLC7A5 (0.93) ALOX15KDM4EHIF1AHSD17B10SLC7A5
Levodopa SCHEMBL30777603 0.86 SLC7A5 (0.93) ALOX15KDM4EHIF1AHSD17B10SLC7A5
Levodopa SCHEMBL11000382 0.85 SLC7A5 (1.00) ALOX15KDM4EHIF1AHSD17B10SLC7A5
Levodopa SCHEMBL116907 0.85 SLC7A5 (1.00) ALOX15KDM4EHIF1AHSD17B10SLC7A5
Levodopa SCHEMBL704089 0.85 SLC7A5 (1.00) ALOX15KDM4EHIF1AHSD17B10SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114171847-B High-flame-retardance high-wettability lithium ion battery diaphragm and preparation method thereof 江苏厚生新能源科技有限公司 2023-09-01 CN claimed
EP-3233077-B1 DOPAMINE D2 RECEPTOR LIGANDS BROAD INST INC (US) 2026-05-06 EP disclosed
US-12424305-B2 Closed-loop AI-optimized EMF treatment and digital delivery of data UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2025-09-23 US disclosed
CN-120076785-A Cosmetic composition for inducing melanin synthesis in individuals or animals, preparation method, cosmetic method and use 科曼宁有限责任公司 2025-05-30 CN disclosed
EP-4532699-A1 TRIPLE TISSUE CULTURE FUSION IMBA-Institut für Molekulare Biotechnologie GmbH (AT) 2025-04-09 EP disclosed
WO-2024218296-A1 COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF LEUCINE-RICH REPEAT KINASE 2 (LRRK2) INHIBITORS H. LUNDBECK A/S (DK) 2024-10-24 WO disclosed
WO-2023233002-A1 TRIPLE TISSUE CULTURE FUSION IMBA - INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) 2023-12-07 WO disclosed
CN-105392500-B Imaging neurological diseases 通用电气健康护理有限公司 2023-08-18 CN disclosed
WO-2023117812-A1 MEMBRANE COATED WITH POLYDOPAMINE AND CHONDROITIN AND PROCESS FOR PRODUCING SAME GAMBRO LUNDIA AB (SE) 2023-06-29 WO disclosed
US-20230157985-A1 METHODS FOR TREATMENT OF PARKINSON'S DISEASE NEURODERM, LTD. (IL) 2023-05-25 US disclosed
US-11498896-B2 Dopamine D2 receptor ligands THE BROAD INSTITUTE, INC. (US) 2022-11-15 US disclosed
CN-111647279-B Aging-resistant functionalized montmorillonite modified asphalt and preparation method thereof 长沙理工大学 2022-06-03 CN disclosed
WO-2021044420-A1 LIQUID COMPOSITIONS COMPRISING A LEVODOPA AMINO ACID CONJUGATE AND USES THEREOF NEURODERM, LTD. (IL) 2021-03-11 WO disclosed
WO-2020035853-A1 PROCESS FOR PREPARING PURIFIED LEVODOPAMIDE FREE BASE NEURODERM, LTD. (IL) 2020-02-20 WO disclosed
WO-2020035853-A1 PROCESS FOR PREPARING PURIFIED LEVODOPAMIDE FREE BASE NEURODERM, LTD. (IL) 2020-02-20 WO disclosed
WO-2019038639-A1 CRYSTALLINE LEVODOPA AMIDE FREE BASE AND METHODS OF MAKING AND USING SAME NEURODERM LTD (IL) 2019-02-28 WO disclosed
WO-2019038637-A1 CRYSTALLINE SALT FORMS OF LEVODOPA AMIDE AND METHODS OF MAKING AND USING SAME NEURODERM LTD (IL) 2019-02-28 WO disclosed
WO-2019038638-A1 PROCESS FOR PREPARING PURIFIED LEVODOPA AMIDE NEURODERM LTD (IL) 2019-02-28 WO disclosed
WO-2019038638-A1 PROCESS FOR PREPARING PURIFIED LEVODOPA AMIDE NEURODERM LTD (IL) 2019-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11498896-B2 Dopamine D2 receptor ligands DRD2, SLC6A3, NTSR2 ALOX15 2824/4885KDM4E 4204/4885HIF1A 2707/4885
US-20230157985-A1 METHODS FOR TREATMENT OF PARKINSON'S DISEASE DDC, DDT, COMT ALOX15 1210/4885KDM4E 3787/4885HIF1A 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.