SCHEMBL21730739

SCHEMBL21730739

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3cccc(-c4ccc5c(c4)Cc4ccccc4-5)c3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.43
MMP12 P39900 1/20 0.43
MMP13 P45452 1/20 0.43
TDP2 O95551 4/20 0.43
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
SRD5A2 P31213 1/20 0.42
CYP1A2 P05177 4/20 0.42
CYP3A4 P08684 4/20 0.42
CYP2C19 P33261 3/20 0.42
CYP2D6 P10635 2/20 0.42
CYP2C9 P11712 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC6A2 P23975 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19239124 0.92 MMP12 (0.40) CNR1MMP12MMP13TDP2ALDH1A1
SCHEMBL19239125 0.92 CYP1A2 (0.43) CNR1MMP12MMP13TDP2ALDH1A1
SCHEMBL14018411 0.91 TDP2 (0.41) CNR1MMP12MMP13TDP2ALDH1A1
SCHEMBL25806782 0.91 CYP1A2 (0.49) CNR1MMP12MMP13TDP2ALDH1A1
SCHEMBL5446075 0.91 CYP1A2 (0.49) MMP12MMP13TDP2ALDH1A1MAPT
SCHEMBL24923295 0.91 CYP1A2 (0.49) CNR1MMP12MMP13TDP2ALDH1A1
SCHEMBL804482 0.91 CYP1A2 (0.49) CNR1MMP12MMP13TDP2ALDH1A1
SCHEMBL25000680 0.91 ALDH1A1 (0.38) CNR1MMP12MMP13TDP2ALDH1A1
SCHEMBL10110906 0.89 TDP2 (0.47) MMP12MMP13TDP2ALDH1A1MAPT
SCHEMBL14016099 0.88 CYP1A2 (0.45) MMP12MMP13TDP2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020036459-A1 POLYMER, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-20 WO disclosed