SCHEMBL10110906

SCHEMBL10110906

c1ccc(N(c2ccccc2)c2ccc(-c3ccc4c(c3)Cc3cc(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)ccc3-4)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 11/20 0.47
MMP12 P39900 1/20 0.41
MMP13 P45452 1/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PARP10 Q53GL7 1/20 0.39
PARP11 Q9NR21 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25557761 0.91 TDP2 (0.42) TDP2MMP12MMP13KDM4EALDH1A1
SCHEMBL13930207 0.89 TDP2 (0.40) TDP2MMP12MMP13KDM4EALDH1A1
SCHEMBL13930208 0.89 TDP2 (0.40) TDP2MMP12MMP13KDM4EALDH1A1
SCHEMBL15481325 0.89 TDP2 (0.40) TDP2MMP12MMP13KDM4EALDH1A1
SCHEMBL21730739 0.89 CNR1 (0.43) TDP2MMP12MMP13KDM4EALDH1A1
SCHEMBL12900066 0.89 TDP2 (0.40) TDP2MMP12MMP13KDM4EALDH1A1
SCHEMBL5446075 0.88 CYP1A2 (0.49) TDP2MMP12MMP13KDM4EALDH1A1
SCHEMBL26240139 0.88 MAPT (0.43) TDP2MMP12MMP13KDM4EALDH1A1
SCHEMBL14018411 0.88 TDP2 (0.41) TDP2MMP12MMP13KDM4EALDH1A1
SCHEMBL17904107 0.88 CYP1A2 (0.44) TDP2MMP12MMP13KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
EP-3960744-A1 CYCLOALKANE-CONDENSED POLYCYCLIC AROMATIC COMPOUND Kwansei Gakuin Educational Foundation (JP) 2022-03-02 EP disclosed
US-20220037591-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-03 US disclosed
US-20210395274-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-12-23 US disclosed
WO-2021230133-A1 POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2021-11-18 WO disclosed
US-20150275015-A1 COMPOSITION FOR FORMING CONDUCTIVE FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-01 US disclosed
US-20150275015-A1 COMPOSITION FOR FORMING CONDUCTIVE FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-01 US disclosed
US-8866134-B2 Light-emitting device and photovoltaic cell, and method for manufacturing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-21 US disclosed
US-8866134-B2 Light-emitting device and photovoltaic cell, and method for manufacturing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-21 US disclosed
US-20130099224-A1 LIGHT-EMITTING DEVICE AND PHOTOVOLTAIC CELL, AND METHOD FOR MANUFACTURING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-25 US disclosed
US-20130099224-A1 LIGHT-EMITTING DEVICE AND PHOTOVOLTAIC CELL, AND METHOD FOR MANUFACTURING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-04-25 US disclosed
US-20130018155-A1 METAL COMPOSITES AND COMPOUND USEFUL FOR PREPARATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-17 US disclosed
US-20130018155-A1 METAL COMPOSITES AND COMPOUND USEFUL FOR PREPARATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-17 US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 TDP2 3731/4885MMP12 4055/4885MMP13 3140/4885
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR TDP2 3586/4885MMP12 4739/4885MMP13 4477/4885
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 TDP2 2869/4885MMP12 4444/4885MMP13 4090/4885
US-20130018155-A1 METAL COMPOSITES AND COMPOUND USEFUL FOR PREPARATION THEREOF TERB1, TELO2, MRPS22 TDP2 3275/4885MMP12 3054/4885MMP13 3453/4885
US-20220037591-A1 Polycyclic aromatic compound F11, C1R, RNF31 TDP2 3731/4885MMP12 4055/4885MMP13 3140/4885
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF CDH1, EPCAM, CD4 TDP2 4554/4885MMP12 3211/4885MMP13 4664/4885
US-20210395274-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION ARNT, TYR, NLRP3 TDP2 2869/4885MMP12 4444/4885MMP13 4090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.