Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | BLK | P51451 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21731428 | 0.82 | KDM4E (0.43) | KDM4EGAAMAPTL3MBTL1ITGB1 | |
| SCHEMBL21731373 | 0.78 | GAA (0.43) | KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL21682616 | 0.77 | MAPT (0.47) | KDM4EGAAMAPTL3MBTL1KDM1A | |
| SCHEMBL7971464 | 0.77 | GAA (0.45) | KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL21731372 | 0.75 | GAA (0.40) | KDM4EGAAMAPTL3MBTL1KDM1A | |
| SCHEMBL21723209 | 0.73 | KDM4E (0.39) | KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL21723173 | 0.73 | GAA (0.41) | KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL21731410 | 0.73 | GAA (0.41) | KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL17674597 | 0.73 | GAA (0.41) | KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL21731414 | 0.72 | KDM4E (0.41) | KDM4EGAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035565-A1 | PESTICIDALLY-ACTIVE MESOIONIC BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-02-20 | — | — | WO | disclosed |