Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491244 | 0.83 | AOC3 (0.47) | AOC3POLBAPOBEC3AAPOBEC3GTAAR1 | |
| SCHEMBL28740896 | 0.82 | AOC3 (0.41) | AOC3TAAR1SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL6490879 | 0.81 | AOC3 (0.41) | AOC3POLBAPOBEC3AAPOBEC3GTAAR1 | |
| SCHEMBL6487531 | 0.81 | AOC3 (0.66) | AOC3TAAR1MAOAHTR2AHRH1 | |
| SCHEMBL21731485 | 0.79 | AOC3 (0.44) | AOC3SIGMAR1HTR2AHRH1ALDH1A1 | |
| SCHEMBL3824994 | 0.78 | AOC3 (0.43) | AOC3TAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL6477129 | 0.78 | AOC3 (0.38) | AOC3HTR2AHRH1ALDH1A1LMNA | |
| SCHEMBL6487412 | 0.78 | AOC3 (0.40) | AOC3POLBAPOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL2399169 | 0.76 | TSHR (0.45) | AOC3POLBAPOBEC3AAPOBEC3GSLC6A2 | |
| SCHEMBL92732 | 0.76 | POLB (0.52) | AOC3POLBAPOBEC3AAPOBEC3GSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456201-B2 | Pharmaceutically active compounds and methods of use | LABORATOIRES SERONO SA (CH) | 2008-11-25 | — | — | US | disclosed |
| EP-1441724-B8 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | SERONO LAB (CH) | 2007-10-17 | — | — | EP | disclosed |
| EP-1441724-B1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | APPLIED RESEARCH SYSTEMS (AN) | 2007-09-05 | — | — | EP | disclosed |
| EP-1282418-B1 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | APPLIED RESEARCH SYSTEMS (AN) | 2005-08-17 | — | — | EP | disclosed |
| US-6914069-B2 | Pharmaceutically active compounds and methods of use | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-07-05 | — | — | US | disclosed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |
| US-6887863-B2 | Hydrazide and alkoxyamide angiogenesis inhibitors | ABBOTT LABORATORIES (US) | 2005-05-03 | — | — | US | disclosed |
| US-20050026985-A1 | Pharmaceutically active compounds and methods of use | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. | 2005-02-03 | — | — | US | disclosed |
| EP-1272456-B1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2004-10-27 | — | — | EP | disclosed |
| US-20040198799-A1 | Methods of increasing endogenous testosterone levels | LABORATOIRES SERONO SA (CH) | 2004-10-07 | — | — | US | disclosed |
| US-20040167126-A1 | Hydrazide and alkoxyamide angiogenesis inhibitors | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| EP-1441724-A1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | Applied Research Systems ARS Holding S.A. (AN) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003026649-A1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-04-03 | — | — | WO | disclosed |
| EP-1282418-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | Serono Reproductive Biology Institute, Inc. (US) | 2003-02-12 | — | — | EP | disclosed |
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| US-20020132844-A1 | Pharmaceutically active compounds and methods of use | MERCK SERONO SA (CH) | 2002-09-19 | — | — | US | disclosed |
| US-20020002152-A1 | Hydrazide and alkoxyamide angiogenesis inhibitors | ABBOTT LABORATORIES | 2002-01-03 | — | — | US | disclosed |
| WO-2001087287-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198799-A1 | Methods of increasing endogenous testosterone levels | SHBG, CYP17A1, NR5A1 | AOC3 885/4885POLB 1754/4885APOBEC3A 3287/4885 |
| US-20040167126-A1 | Hydrazide and alkoxyamide angiogenesis inhibitors | METAP2, METAP1, ANPEP | AOC3 1365/4885POLB 1563/4885APOBEC3A 4171/4885 |
| US-20020132844-A1 | Pharmaceutically active compounds and methods of use | CATSPER1, NASP, ACR | AOC3 1718/4885POLB 1566/4885APOBEC3A 717/4885 |
| US-20050026985-A1 | Pharmaceutically active compounds and methods of use | CATSPER1, NASP, ACR | AOC3 1718/4885POLB 1566/4885APOBEC3A 717/4885 |
| US-20020002152-A1 | Hydrazide and alkoxyamide angiogenesis inhibitors | METAP2, METAP1, ANPEP | AOC3 1365/4885POLB 1563/4885APOBEC3A 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.