SCHEMBL21733156

SCHEMBL21733156

CCn1cnc2nc(Cl)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRPS1 P60891 1/20 0.44
PTGER4 P35408 1/20 0.41
NPC1 O15118 10/20 0.40
RAB9A P51151 9/20 0.40
ADORA2A P29274 1/20 0.38
KMT2A Q03164 4/20 0.35
GAA P10253 2/20 0.35
MEN1 O00255 2/20 0.35
KDM4E B2RXH2 7/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 5/20 0.35
ALDH1A1 P00352 4/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TP53 P04637 3/20 0.33
HTT P42858 2/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
CDK1 P06493 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869023 0.76 PRPS1 (0.51) PRPS1GAASMN1; SMN2MAPTALDH1A1
SCHEMBL23529932 0.76 PRPS1 (0.41) PRPS1PTGER4NPC1RAB9AKMT2A
SCHEMBL29492199 0.76 PRPS1 (0.41) PRPS1PTGER4NPC1RAB9AKMT2A
SCHEMBL27452147 0.75 KDM4E (0.38) NPC1RAB9AADORA2AKMT2AGAA
SCHEMBL25330377 0.75 PRPS1 (0.38) PRPS1NPC1MAPTSRC
SCHEMBL20665100 0.71 HCAR3 (0.40) PRPS1NPC1RAB9AADORA2AKMT2A
SCHEMBL20665101 0.71 SLC2A1 (0.37) PRPS1PTGER4
SCHEMBL231309 0.70 LTA4H (0.48) NPC1RAB9AADORA2AKMT2AGAA
SCHEMBL17463071 0.69 PTGER4 (0.41) PTGER4NPC1RAB9AKMT2AGAA
SCHEMBL11335130 0.68 NPC1 (0.41) PRPS1NPC1RAB9AADORA2AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106949-A1 WRN INHIBITORS RADD PHARMACEUTICALS, INC. (US) 2025-05-22 WO disclosed
EP-3402797-B1 HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2020-02-19 EP disclosed