Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRPS1 | P60891 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863634 | 0.76 | FGFR1 (0.40) | PRPS1MAPTHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL21733156 | 0.76 | PRPS1 (0.44) | PRPS1MAPTHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL4863437 | 0.75 | LTA4H (0.49) | MAPTHSD17B10LTA4HSMN1; SMN2LMNA | |
| SCHEMBL23529932 | 0.73 | PRPS1 (0.41) | PRPS1MAPTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL29492199 | 0.73 | PRPS1 (0.41) | PRPS1MAPTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8088090 | 0.73 | MAPT (0.56) | PRPS1MAPTHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL11250423 | 0.70 | LTA4H (0.50) | MAPTHSD17B10LTA4HSMN1; SMN2LMNA | |
| SCHEMBL23227792 | 0.69 | PRPS1 (1.00) | PRPS1 | |
| SCHEMBL6851027 | 0.68 | TDP1 (0.70) | MAPTHSD17B10SMN1; SMN2LMNAALOX15 | |
| Hydrochloric Acid SCHEMBL20471683 | 0.68 | PRPS1 (0.98) | PRPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313101-B1 | ANTIBIOTICS | AVENTIS PHARMA S.A. (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1026170-A1 | Erythromycin derivatives, their preparation and use as medicaments | HOECHST MARION ROUSSEL (FR) | 2000-08-09 | — | — | EP | disclosed |