Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 3/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21733792 | 0.83 | LMNA (0.35) | ALDH1A1MEN1KMT2AFABP4FABP3 | |
| SCHEMBL21733724 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL21733481 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL26694482 | 0.75 | MEN1 (0.42) | ALDH1A1MEN1KMT2AGAAFABP4 | |
| SCHEMBL24649338 | 0.74 | LMNA (0.39) | ALDH1A1MEN1KMT2AGAAFABP4 | |
| SCHEMBL1860490 | 0.74 | PIK3CD (0.42) | ALDH1A1MEN1KMT2AGAAFABP4 | |
| SCHEMBL30708362 | 0.74 | PIK3CD (0.42) | ALDH1A1MEN1KMT2AGAAFABP4 | |
| SCHEMBL1862955 | 0.71 | LMNA (0.40) | ALDH1A1MEN1KMT2AGAAFABP4 | |
| SCHEMBL21733856 | 0.71 | CACNA1S (0.33) | ALDH1A1MEN1KMT2AGAAFABP4 | |
| SCHEMBL26694500 | 0.70 | APLNR (0.42) | ALDH1A1MEN1KMT2AGAAFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760744-B2 | Fused ring compounds | GENENTECH, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| WO-2020035031-A1 | FUSED RING COMPOUNDS | GENENTECH, INC. (US) | 2020-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760744-B2 | Fused ring compounds | KRAS, NRAS, HRAS | ALDH1A1 3678/4885MEN1 2354/4885KMT2A 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.