Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 3/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22628732 | 0.89 | POLB (0.33) | CA2PDK2ESR1ESR2 | |
| SCHEMBL21735326 | 0.78 | FGFR1 (0.33) | ESR1ESR2 | |
| SCHEMBL21735473 | 0.77 | THRB (0.37) | PPARAPDK2ESR1ESR2PPARD | |
| SCHEMBL21735526 | 0.77 | POLB (0.38) | CA2PDK2ESR1ESR2 | |
| SCHEMBL21735522 | 0.77 | PDK2 (0.40) | PDK2ESR1ESR2 | |
| SCHEMBL22628791 | 0.77 | — | — | |
| SCHEMBL21735000 | 0.76 | NR1H4 (0.38) | CA2PPARAESR1ESR2CACNA1H | |
| SCHEMBL22628825 | 0.76 | PDK2 (0.34) | PDK2ESR1ESR2CACNA1BPPARG | |
| SCHEMBL21735456 | 0.75 | THRB (0.37) | PPARAPDK2ESR1ESR2 | |
| SCHEMBL21734995 | 0.74 | THRB (0.41) | CA2PPARAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | CA2 3899/4885PPARA 581/4885PDK2 3949/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | CA2 3899/4885PPARA 581/4885PDK2 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.