Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28239769 | 0.89 | MPO (0.44) | MKNK1MKNK2OPRM1OPRL1 | |
| SCHEMBL14026218 | 0.86 | OPRM1 (0.46) | OPRM1OPRL1 | |
| SCHEMBL20757564 | 0.81 | CHRNB2 (0.43) | OPRM1OPRL1 | |
| SCHEMBL31737023 | 0.78 | SLC18A3 (0.47) | HRH4SLC18A3SIGMAR1HRH3 | |
| SCHEMBL18740585 | 0.78 | USP7 (0.50) | OPRM1OPRL1HRH4SLC18A3SIGMAR1 | |
| SCHEMBL31127661 | 0.78 | OPRM1 (0.41) | OPRM1OPRL1HRH4SLC18A3SIGMAR1 | |
| SCHEMBL171433 | 0.78 | HRH4 (0.39) | MKNK1MKNK2HRH4SLC18A3SIGMAR1 | |
| SCHEMBL3063348 | 0.78 | OPRM1 (0.41) | OPRM1OPRL1HRH4SLC18A3SIGMAR1 | |
| SCHEMBL171235 | 0.78 | HRH4 (0.46) | MKNK1MKNK2HRH4SLC18A3SIGMAR1 | |
| SCHEMBL2885151 | 0.78 | HTR3A (0.46) | SLC6A2SLC6A4HTR1AHRH4SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352357-B2 | Cycloalkylurea derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-06-07 | — | — | US | disclosed |
| US-20220081441-A1 | CYCLOALKYLUREA DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-03-17 | — | — | US | disclosed |
| US-7973056-B2 | Triazole derivative or salt thereof | FUJIFILM FINECHEMICALS CO., LTD (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20100324049-A1 | DIARYL KETIMINE DERIVATIVE HAVING ANTAGONISM AGAINST MELANIN-CONCENTRATING HORMONE RECEPTOR | MSD K.K. (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20100324049-A1 | DIARYL KETIMINE DERIVATIVE HAVING ANTAGONISM AGAINST MELANIN-CONCENTRATING HORMONE RECEPTOR | MSD K.K. (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20090299071-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-2128155-A1 | Triazole derivative or salt thereof | Fujifilm Finechemicals Co. Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324049-A1 | DIARYL KETIMINE DERIVATIVE HAVING ANTAGONISM AGAINST MELANIN-CONCENTRATING HORMONE RECEPTOR | MC1R, MCHR1, MCHR2 | MKNK1 1433/4885MKNK2 1886/4885SLC6A2 545/4885 |
| US-11352357-B2 | Cycloalkylurea derivative | HCRTR2, HCRTR1, CRHR2 | MKNK1 2643/4885MKNK2 2205/4885SLC6A2 366/4885 |
| US-20090299071-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | HDAC3, JAK2, STAT3 | MKNK1 3669/4885MKNK2 3384/4885SLC6A2 1133/4885 |
| US-20220081441-A1 | CYCLOALKYLUREA DERIVATIVE | HCRTR2, HCRTR1, CRHR2 | MKNK1 2643/4885MKNK2 2205/4885SLC6A2 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.