Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735369 | 0.92 | S1PR1 (0.37) | S1PR1S1PR3PTGESALOX5THRB | |
| SCHEMBL22624927 | 0.91 | NPC1 (0.34) | S1PR1S1PR3ACHE | |
| SCHEMBL21734935 | 0.91 | S1PR1 (0.42) | S1PR1S1PR3PTGESALOX5 | |
| SCHEMBL21734937 | 0.91 | S1PR1 (0.36) | S1PR1S1PR3PTGESALOX5 | |
| SCHEMBL21735368 | 0.90 | THRB (0.40) | S1PR1S1PR3PTGESALOX5THRB | |
| SCHEMBL21735505 | 0.87 | S1PR1 (0.37) | S1PR1S1PR3PTGESALOX5ACHE | |
| SCHEMBL22630095 | 0.87 | S1PR1 (0.36) | S1PR1S1PR3PTGESALOX5ACHE | |
| SCHEMBL21735355 | 0.86 | NPC1 (0.33) | S1PR1S1PR3 | |
| SCHEMBL21735052 | 0.85 | S1PR1 (0.36) | S1PR1S1PR3PTGESALOX5 | |
| SCHEMBL22625122 | 0.85 | STS (0.34) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3583091-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | S1PR1 3951/4885S1PR3 2314/4885PTGES 1411/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | S1PR1 3951/4885S1PR3 2314/4885PTGES 1411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.