Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21735403 | 0.90 | MTNR1A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL21735163 | 0.85 | POLB (0.34) | CYP11B1CYP11B2CYP19A1AHR | |
| SCHEMBL21735488 | 0.81 | MTNR1A (0.32) | CYP11B1CYP11B2CYP19A1AHRP4HTM | |
| SCHEMBL21735282 | 0.79 | HDAC1 (0.37) | CYP11B1CYP11B2CYP19A1P4HTMNPC1 | |
| SCHEMBL21735510 | 0.79 | CYP11B1 (0.33) | CYP11B1CYP11B2CYP19A1AHRALOX5AP | |
| SCHEMBL21735395 | 0.79 | CYP11B1 (0.36) | CYP11B1CYP11B2CYP19A1AHRMTNR1A | |
| SCHEMBL21735153 | 0.79 | CYP11B1 (0.32) | CYP11B1CYP11B2CYP19A1AHRP4HTM | |
| SCHEMBL21735053 | 0.78 | APP (0.38) | CYP11B1CYP11B2CYP19A1NPC1RAB9A | |
| SCHEMBL21735506 | 0.78 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP19A1AHRP4HTM | |
| SCHEMBL21735545 | 0.76 | MTNR1A (0.39) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | CYP11B1 2888/4885CYP11B2 2816/4885CYP19A1 2317/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | CYP11B1 2888/4885CYP11B2 2816/4885CYP19A1 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.