Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22629014 | 0.87 | HDAC6 (0.34) | HDAC6KLK7MEN1LMNAMAPT | |
| SCHEMBL21735323 | 0.86 | HDAC6 (0.36) | HDAC6FFAR1HIF1AMEN1LMNA | |
| SCHEMBL21735311 | 0.86 | HDAC6 (0.36) | HDAC6KLK7FFAR1HIF1AMEN1 | |
| SCHEMBL21735373 | 0.76 | CYP3A4 (0.34) | MEN1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL21735363 | 0.76 | CYP3A4 (0.34) | MEN1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL21735240 | 0.74 | HDAC6 (0.37) | HDAC6KLK7FFAR1HIF1AMEN1 | |
| SCHEMBL21735237 | 0.74 | HDAC6 (0.37) | HDAC6FFAR1HIF1AMEN1LMNA | |
| SCHEMBL21735844 | 0.74 | SRD5A1 (0.34) | KLK7CYP3A4SMN1; SMN2 | |
| SCHEMBL22628735 | 0.73 | HDAC6 (0.38) | HDAC6KLK7FFAR1MEN1LMNA | |
| SCHEMBL21735503 | 0.72 | RAB9A (0.40) | HDAC6KLK7MEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11014901-B2 | Hydrophobic compounds for optically active devices | MERCK PATENT GMBH (DE) | 2021-05-25 | — | — | US | disclosed |
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055833-A1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | UACA, CRYZ, TRPA1 | HDAC6 1975/4885KLK7 2762/4885FFAR1 1590/4885 |
| US-11014901-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | HDAC6 1975/4885KLK7 2762/4885FFAR1 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.