SCHEMBL21736065

SCHEMBL21736065

c1ccc(-c2ccc3oc4nc(-c5ccccc5)nc(-n5c6ccccc6c6cc7ccccc7cc65)c4c3c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBK1 Q9UHD2 1/20 0.34
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
PGR P06401 1/20 0.32
LMNA P02545 3/20 0.31
KDM4E B2RXH2 2/20 0.31
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21736055 0.93 SMN1; SMN2 (0.34) TBK1PLA2G2APLA2G4AGAAL3MBTL1
SCHEMBL21735860 0.91 TSHR (0.37) L3MBTL1TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL21736073 0.91 ALDH1A1 (0.34) L3MBTL1TSHRSMN1; SMN2KDM4EMAPT
SCHEMBL21735923 0.90 CYP1A2 (0.41) TSHRMEN1KMT2APGRLMNA
SCHEMBL21735869 0.90 TSHR (0.33) PLA2G2APLA2G4ATSHRSMN1; SMN2MEN1
SCHEMBL20669801 0.88 SMN1; SMN2 (0.33) L3MBTL1TSHRSMN1; SMN2MEN1KMT2A
SCHEMBL24772668 0.88 CHEK2 (0.37) L3MBTL1SMN1; SMN2MEN1KMT2ANPC1
SCHEMBL21736240 0.88 SIRT2 (0.32) L3MBTL1SMN1; SMN2LMNAKDM4E
SCHEMBL21736008 0.87 SMN1; SMN2 (0.32) L3MBTL1SMN1; SMN2LMNAKDM4EPIM1
SCHEMBL21735901 0.86 CHEK2 (0.31) L3MBTL1SMN1; SMN2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11530225-B2 Compound and organic light-emitting diode comprising same LG CHEM, LTD. (KR) 2022-12-20 US disclosed
EP-3553049-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME LG CHEMICAL LTD (KR) 2022-01-19 EP disclosed
US-20200055865-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2020-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530225-B2 Compound and organic light-emitting diode comprising same CRY1, CRY2, TRPA1 TBK1 2762/4885PLA2G2A 4335/4885PLA2G4A 4197/4885
US-20200055865-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME CRY1, CRY2, TRPA1 TBK1 2762/4885PLA2G2A 4335/4885PLA2G4A 4197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.