Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174736 | 0.86 | PTGS2 (0.49) | PTGS2FAAH | |
| SCHEMBL3210607 | 0.85 | NAAA (0.49) | PTGS2NAAA | |
| SCHEMBL2174614 | 0.84 | PTGS2 (0.47) | PTGS2FAAH | |
| SCHEMBL3150081 | 0.83 | PTGS2 (0.45) | PTGS2NAAAMMP2MMP9MMP8 | |
| SCHEMBL3150086 | 0.83 | PTGS2 (0.45) | PTGS2NAAAMMP2MMP9MMP8 | |
| SCHEMBL2175704 | 0.83 | PTGS2 (0.47) | PTGS2FAAH | |
| SCHEMBL2174987 | 0.82 | PTGS2 (0.46) | PTGS2FAAH | |
| SCHEMBL5274109 | 0.81 | PTGS2 (0.45) | PTGS2NAAAMMP2MMP9MMP8 | |
| SCHEMBL3439039 | 0.80 | PTGS2 (0.44) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL3439038 | 0.80 | PTGS2 (0.44) | PTGS2MMP2MMP9MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |