Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174736 | 0.89 | PTGS2 (0.49) | PTGS2FAAH | |
| SCHEMBL2174614 | 0.87 | PTGS2 (0.47) | PTGS2FAAH | |
| SCHEMBL2175704 | 0.86 | PTGS2 (0.47) | PTGS2FAAH | |
| SCHEMBL2175781 | 0.84 | PLG (0.43) | PTGS2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2175784 | 0.84 | PLG (0.43) | PTGS2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2174444 | 0.83 | PLG (0.42) | PTGS2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2174447 | 0.83 | PLG (0.42) | PTGS2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2173697 | 0.82 | PTGS2 (0.51) | PTGS2FAAH | |
| SCHEMBL2174985 | 0.81 | PLG (0.42) | PTGS2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2176885 | 0.80 | PLG (0.40) | PTGS2PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |