Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174736 | 0.91 | PTGS2 (0.49) | PTGS2FAAH | |
| SCHEMBL2175704 | 0.87 | PTGS2 (0.47) | PTGS2FAAH | |
| SCHEMBL2174987 | 0.87 | PTGS2 (0.46) | PTGS2FAAH | |
| SCHEMBL2175148 | 0.84 | PTGS2 (0.42) | PTGS2SIRT2SIRT1MEN1ALDH1A1 | |
| SCHEMBL2175152 | 0.84 | PTGS2 (0.42) | PTGS2SIRT2SIRT1MEN1ALDH1A1 | |
| SCHEMBL2173697 | 0.84 | PTGS2 (0.51) | PTGS2FAAH | |
| SCHEMBL2173921 | 0.83 | ITGB3 (0.43) | PTGS2 | |
| SCHEMBL2173924 | 0.83 | ITGB3 (0.43) | PTGS2 | |
| SCHEMBL2174613 | 0.82 | ITGB3 (0.42) | PTGS2SIRT2SIRT1MEN1ALDH1A1 | |
| SCHEMBL3210607 | 0.81 | NAAA (0.49) | PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |