Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5882272 | 0.80 | ALDH1A1 (0.58) | TTRALDH1A1NPSR1TSHRFDPS | |
| SCHEMBL11714137 | 0.79 | L3MBTL1 (0.50) | ALDH1A1NPSR1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL31726405 | 0.78 | MAOA (0.43) | TTRALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL5113878 | 0.78 | TTR (0.55) | TTRALDH1A1NPSR1TSHRFDPS | |
| SCHEMBL23585595 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL26145059 | 0.77 | CA12 (0.53) | TTRALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL3888294 | 0.76 | L3MBTL1 (0.55) | ALDH1A1MAPTSMN1; SMN2RAB9AHTT | |
| SCHEMBL3397850 | 0.75 | RAB9A (0.46) | ALDH1A1NPSR1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL11709880 | 0.75 | PTPRG (0.48) | ALDH1A1NPSR1SMN1; SMN2RAB9ANPC1 | |
| Formaldehyde SCHEMBL28320418 | 0.75 | RAB9A (0.51) | ALDH1A1NPSR1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294732-B | Pharmaceutical compound for treating liver diseases and application thereof | 江苏新元素医药科技有限公司 | 2021-10-26 | — | — | CN | disclosed |
| WO-2020035058-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATING LIVER DISEASES AND APPLICATION THEREOF | 江苏新元素医药科技有限公司 | 2020-02-20 | — | — | WO | disclosed |
| CN-110294732-A | Medical compounds and its application for treating hepatopathy | 江苏新元素医药科技有限公司 | 2019-10-01 | — | — | CN | disclosed |