SCHEMBL217391

SCHEMBL217391

CCCCC1=C(C)c2ccccc2[CH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
GPR3 P46089 1/20 0.34
SETD7 Q8WTS6 1/20 0.34
LIPG Q9Y5X9 1/20 0.33
SKP2 Q13309 1/20 0.33
PTPN1 P18031 1/20 0.33
TLR8 Q9NR97 1/20 0.33
HSD11B1 P28845 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
GCGR P47871 1/20 0.31
ELANE P08246 1/20 0.31
CTSG P08311 1/20 0.31
PSMB5 P28074 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TYR P14679 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217321 0.89 NR1H2 (0.33) NR1H2NR1H3SETD7
SCHEMBL2871080 0.81 NR1H2 (0.34) NR1H2NR1H3GPR3SETD7LIPG
SCHEMBL218144 0.80 MAP2K7 (0.33) SETD7PTPN1BCHEACHECYP3A4
SCHEMBL2974719 0.76 NR1H2 (0.40) NR1H2NR1H3GPR3SETD7LIPG
SCHEMBL2975456 0.75 NR1H2 (0.42) NR1H2NR1H3GPR3SETD7LIPG
SCHEMBL2972911 0.74 NR1H2 (0.33) NR1H2NR1H3PSMB5
SCHEMBL2975093 0.73 NR1H2 (0.33) NR1H2NR1H3
SCHEMBL2974487 0.73 NR1H2 (0.33) NR1H2NR1H3SETD7
SCHEMBL2970259 0.73 NR1H2 (0.33) NR1H2NR1H3ELANECTSG
SCHEMBL8022504 0.71 NR1H2 (0.42) NR1H2NR1H3LIPGTLR8CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-9409834-B2 Low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-09 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
EP-1910432-B1 PROCESS TO PRODUCE LOW VISCOSITY POLY-ALPHA-OLEFINS EXXONMOBIL CHEM PATENTS INC (US) 2014-11-12 EP disclosed
US-20090036725-A1 Process To Produce Polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. 2009-02-05 US disclosed
WO-2009017953-A2 PROCESS TO PRODUCE POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENT INC. (US) 2009-02-05 WO disclosed
US-20090005279-A1 Polyalpha-Olefin Compositions and Processes to Produce the Same EXXONMOBIL CHEMICAL PATENTS INC. 2009-01-01 US disclosed
WO-2008140875-A1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-20 WO disclosed
US-20080287617-A1 Catalyst System For Olefin Polymerization And Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2008-11-20 US disclosed
US-20080177121-A1 Process to produce high viscosity fluids EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-24 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036725-A1 Process To Produce Polyalphaolefins KCNMA1, F10, AP2A1 NR1H2 2979/4885NR1H3 2881/4885GPR3 4414/4885
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins AP1M1, AP3D1, AP3M1 NR1H2 4399/4885NR1H3 3916/4885GPR3 4502/4885
US-20080177121-A1 Process to produce high viscosity fluids SCO2, POLI, TAOK1 NR1H2 4701/4885NR1H3 4574/4885GPR3 4063/4885
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 NR1H2 1747/4885NR1H3 1077/4885GPR3 4259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.