SCHEMBL21740700

SCHEMBL21740700

c1ccc(-n2c3ccccc3c3ccc4c5ccccc5n(-c5ccc6c(c5)oc5cc(-c7nc(-c8ccc9ccccc9c8)nc(-c8ccc9ccccc9c8)n7)ccc56)c4c32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34
TUBB6 Q9BUF5 1/20 0.34
TUBB2B Q9BVA1 1/20 0.34
TUBB1 Q9H4B7 1/20 0.34
MAPK9 P45984 2/20 0.33
MAPK10 P53779 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21883182 0.95 SIRT2 (0.38) KDM4EATML3MBTL1TUBB4ATUBB
SCHEMBL23740611 0.92 CYP1A1 (0.35) KDM4ETUBB4ATUBBTUBA3CTUBA1B
SCHEMBL21883207 0.92 L3MBTL1 (0.40) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL22049208 0.91 KDM4E (0.35) KDM4EATML3MBTL1TUBB4ATUBB
SCHEMBL23740529 0.91 CYP1A2 (0.36) KDM4ETUBB4ATUBBTUBA3CTUBA1B
SCHEMBL21740868 0.91 TUBB4A (0.38) KDM4EATML3MBTL1TUBB4ATUBB
SCHEMBL23740486 0.90 CYP1A2 (0.36) KDM4ETUBB4ATUBBTUBA3CTUBA1B
SCHEMBL21668780 0.90 KDM4E (0.39) KDM4EATML3MBTL1TUBB4ATUBB
SCHEMBL22596009 0.90 KDM4E (0.44) KDM4EATML3MBTL1TUBB4ATUBB
SCHEMBL24118991 0.89 KDM4E (0.33) KDM4EL3MBTL1TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element LT MATERIALS CO., LTD. (KR) 2022-07-12 US disclosed
US-20210057651-A1 ORGANIC LIGHT EMITTING DEVICE, METHOD FOR MANUFACTURING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO., LTD. (KR) 2021-02-25 US disclosed
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2020-12-03 US disclosed
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT HEESUNG MATERIAL LTD. (KR) 2020-04-16 US disclosed
EP-3611173-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT Heesung Material Ltd. (KR) 2020-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element CRY1, CYBA, L1CAM KDM4E 3489/4885ATM 2594/4885L3MBTL1 838/4885
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT CRY1, CYBA, L1CAM KDM4E 3489/4885ATM 2594/4885L3MBTL1 838/4885
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 KDM4E 2341/4885ATM 2995/4885L3MBTL1 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.