Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580366 | 0.71 | CYP3A4 (0.34) | ALDH1A1HSD17B10 | |
| SCHEMBL5544044 | 0.71 | ALDH1A1 (0.33) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL7458773 | 0.70 | ALDH1A1 (0.35) | NPC1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7206719 | 0.70 | ADRA2A (0.36) | NPC1RAB9A | |
| SCHEMBL7206716 | 0.68 | NPC1 (0.33) | NPC1RAB9A | |
| SCHEMBL5544035 | 0.67 | ALDH1A1 (0.33) | NPC1RAB9AKDM4EHKDC1TDP1 | |
| SCHEMBL30002773 | 0.67 | MAPT (0.41) | NPC1RAB9AL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL15278576 | 0.67 | ALDH1A1 (0.33) | ALDH1A1HSD17B10 | |
| SCHEMBL6129371 | 0.67 | MAPT (0.41) | NPC1RAB9AL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL5160632 | 0.66 | ALDH1A1 (0.46) | NPC1RAB9AKDM4EHKDC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036812-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-I\" PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-20 | — | — | WO | disclosed |