Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712312 | 0.80 | DRD2 (0.57) | KDM4ESMN1; SMN2ALDH1A1LTA4HHTT | |
| SCHEMBL6399281 | 0.80 | MEN1 (0.54) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL21741610 | 0.79 | KDM4E (0.62) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL6400429 | 0.78 | KDM4E (0.55) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL6152322 | 0.73 | LTA4H (0.51) | KDM4ESMN1; SMN2ALDH1A1LTA4HNPC1 | |
| SCHEMBL21740126 | 0.72 | MAPT (0.60) | KDM4EALDH1A1RAB9AHRH3 | |
| SCHEMBL6393260 | 0.72 | LTA4H (0.84) | KDM4ESMN1; SMN2ALDH1A1LTA4HNPC1 | |
| SCHEMBL8401002 | 0.70 | DRD2 (0.75) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11365759 | 0.70 | DRD2 (0.75) | KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6154507 | 0.70 | HRH1 (0.50) | KDM4ESMN1; SMN2ALDH1A1LTA4HNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036812-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-I\" PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-20 | — | — | WO | disclosed |