Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ACP1 | P24666 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928911 | 0.82 | ALDH1A1 (0.58) | KDM4EHSD17B10ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11465415 | 0.74 | DRD3 (0.51) | MAPTKDM4EALDH1A1MEN1POLB | |
| SCHEMBL21712312 | 0.74 | DRD2 (0.57) | KDM4EALDH1A1MEN1POLBKMT2A | |
| SCHEMBL8350584 | 0.74 | MAPT (0.62) | MAPTKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL6201353 | 0.74 | MEN1 (0.42) | ACP1RAB9ASMARCA2MEN1POLB | |
| SCHEMBL21741610 | 0.73 | KDM4E (0.62) | MAPTKDM4EALDH1A1L3MBTL1RAB9A | |
| SCHEMBL21741655 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1RAB9AHRH3 | |
| SCHEMBL4931903 | 0.71 | ADRA1A (0.54) | MAPTKDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL10801291 | 0.71 | KDM4E (0.65) | MAPTKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL8877516 | 0.71 | KMT2A (0.45) | MAPTALDH1A1RAB9AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020036574-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-I' PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-20 | — | — | WO | disclosed |