Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.75 |
| ▸ | KRAS | P01116 | 6/20 | 0.71 |
| ▸ | NT5E | P21589 | 1/20 | 0.71 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.70 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.66 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.64 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.64 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.64 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.61 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.59 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HINT1 | P49773 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742886 | 1.00 | TGM2 (0.75) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL21742745 | 0.99 | TGM2 (0.77) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL21742746 | 0.99 | TGM2 (0.77) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL18769114 | 0.93 | TGM2 (0.85) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL29429843 | 0.93 | TGM2 (0.85) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL21067722 | 0.93 | TGM2 (0.85) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL851357 | 0.93 | TGM2 (0.85) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL22001585 | 0.92 | TGM2 (0.69) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL2167315 | 0.92 | TGM2 (0.75) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL1304258 | 0.91 | TGM2 (0.81) | TGM2KRASNT5EFUT5P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696709-B2 | Phosphotriazole MRNA 5′-end cap analogs, composition comprising the same, RNA molecule incorporating the same, uses thereof and method of synthesizing RNA molecule, protein or peptide | UNIWERSYTET WARSZAWSKI (PL) | 2020-06-30 | — | — | US | disclosed |
| US-20200055891-A1 | NOVEL PHOSPHOTRIAZOLE MRNA 5'-END CAP ANALOGS, COMPOSITION COMPRISING THE SAME, RNA MOLECULE INCORPORATING THE SAME, USES THEREOF AND METHOD OF SYNTHESIZING RNA MOLECULE, PROTEIN OR PEPTIDE | UNIWERSYTET WARSZAWSKI (PL) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696709-B2 | Phosphotriazole MRNA 5′-end cap analogs, composition comprising the same, RNA molecule incorporating the same, uses thereof and method of synthesizing RNA molecule, protein or peptide | RNGTT, RNMT, NSUN3 | TGM2 3265/4885KRAS 3243/4885NT5E 1027/4885 |
| US-20200055891-A1 | NOVEL PHOSPHOTRIAZOLE MRNA 5'-END CAP ANALOGS, COMPOSITION COMPRISING THE SAME, RNA MOLECULE INCORPORATING THE SAME, USES THEREOF AND METHOD OF SYNTHESIZING RNA MOLECULE, PROTEIN OR PEPTIDE | RNGTT, RNMT, NSUN3 | TGM2 3588/4885KRAS 3403/4885NT5E 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.