Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21743929 | 0.80 | BTN3A1 (0.41) | ALDH1A1CA12CA9MAPTBTN3A1 | |
| SCHEMBL23077326 | 0.77 | CASP3 (0.40) | ALDH1A1NPSR1MAPT | |
| SCHEMBL23077322 | 0.77 | CASP3 (0.40) | ALDH1A1NPSR1MAPT | |
| SCHEMBL21744324 | 0.76 | ALDH1A1 (0.44) | ALDH1A1NPSR1CA12CA9MEN1 | |
| SCHEMBL28630900 | 0.75 | HPGD (0.39) | NPSR1NPC1RAB9AMAPT | |
| SCHEMBL9609393 | 0.75 | ALOX15 (0.35) | ALDH1A1MAPTBTN3A1 | |
| SCHEMBL21744522 | 0.74 | ALDH1A1 (0.59) | ALDH1A1NPSR1CA12CA9MEN1 | |
| SCHEMBL7746775 | 0.74 | ALDH1A1 (0.59) | ALDH1A1NPSR1CA12CA9MEN1 | |
| SCHEMBL8932545 | 0.74 | KMT2A (0.56) | ALDH1A1CA12CA9MEN1KMT2A | |
| SCHEMBL12903756 | 0.74 | HPGD (0.51) | ALDH1A1NPSR1NPC1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | UNIV EMORY (US) | 2023-04-13 | — | — | US | disclosed |
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | EMORY UNIVERSITY | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054623-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | ALDH1A1 1760/4885NPSR1 791/4885CA12 3520/4885 |
| US-20230112832-A1 | Chemokine CXCR4 Receptor Modulators and Uses Related Thereto | CXCR4, CXCL12, CXCR1 | ALDH1A1 1760/4885NPSR1 791/4885CA12 3520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.