Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2173342 | 0.93 | PTGS2 (0.41) | PTGS2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2173346 | 0.93 | PTGS2 (0.41) | PTGS2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2176316 | 0.93 | PTGS2 (0.41) | PTGS2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2175633 | 0.92 | PTGS2 (0.40) | PTGS2ITGB3ITGAVLTB4R2 | |
| SCHEMBL2175630 | 0.92 | PTGS2 (0.40) | PTGS2ITGB3ITGAVLTB4R2 | |
| SCHEMBL2175536 | 0.90 | PTGS2 (0.40) | PTGS2HDAC1HDAC6PLGPRSS1 | |
| SCHEMBL2175533 | 0.90 | PTGS2 (0.40) | PTGS2HDAC1HDAC6PLGPRSS1 | |
| SCHEMBL2174734 | 0.90 | PTGS2 (0.40) | PTGS2HDAC1HDAC6PLGPRSS1 | |
| SCHEMBL2174613 | 0.87 | ITGB3 (0.42) | PTGS2HDAC1HDAC6PLGPRSS1 | |
| SCHEMBL2174985 | 0.86 | PLG (0.42) | PTGS2HDAC1HDAC6PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973063-B2 | Methods for activating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-07-05 | — | — | US | disclosed |
| EP-1742608-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARϝ-TYPE RECEPTORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005108352-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARϜ-TYPE RECEPTORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-11-17 | — | — | WO | disclosed |