Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468227 | 0.85 | SMARCA2 (0.43) | DRD4S1PR1S1PR3GRIN2BDRD2 | |
| SCHEMBL21747470 | 0.84 | FAAH (0.47) | DRD4S1PR1S1PR3GRIN2BDRD2 | |
| SCHEMBL21747451 | 0.84 | ALDH1A1 (0.49) | DRD4S1PR1S1PR3DRD2NPC1 | |
| SCHEMBL20542002 | 0.82 | MCHR1 (0.45) | DRD4S1PR1S1PR3DRD2FAAH | |
| SCHEMBL20541900 | 0.81 | FAAH (0.50) | DRD4S1PR1S1PR3FAAHNPC1 | |
| SCHEMBL20541620 | 0.80 | S1PR1 (0.45) | DRD4S1PR1S1PR3GRIN2BDRD2 | |
| SCHEMBL20541736 | 0.79 | NPC1 (0.49) | DRD4S1PR1S1PR3FAAHNPC1 | |
| SCHEMBL20541985 | 0.79 | HDAC1 (0.49) | DRD4S1PR1S1PR3FAAH | |
| SCHEMBL20541721 | 0.79 | KDM4E (0.52) | DRD4S1PR1S1PR3FAAHMC4R | |
| SCHEMBL21747444 | 0.79 | S1PR1 (0.50) | S1PR1S1PR3GRIN2BNR1H4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |