Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468244 | 0.86 | ALDH1A1 (0.45) | ALDH1A1PKMLMNAHTTMAPT | |
| SCHEMBL21747449 | 0.84 | DRD4 (0.49) | NPC1DRD4S1PR1S1PR3DRD2 | |
| SCHEMBL21747467 | 0.82 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL20541643 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL21747463 | 0.81 | S1PR1 (0.47) | ALDH1A1PKMLMNAHTTMAPT | |
| SCHEMBL20541846 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTMAPK1L3MBTL1 | |
| SCHEMBL21747470 | 0.80 | FAAH (0.47) | DRD4S1PR1S1PR3DRD2 | |
| SCHEMBL20542002 | 0.79 | MCHR1 (0.45) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL20541900 | 0.78 | FAAH (0.50) | NPC1RAB9ASMN1; SMN2DRD4S1PR1 | |
| SCHEMBL20541620 | 0.77 | S1PR1 (0.45) | ALDH1A1LMNAMAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |