Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | C1R | P00736 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747473 | 0.87 | NPC1 (0.44) | S1PR1S1PR3PDCD1CD274MAPT | |
| SCHEMBL30468237 | 0.87 | GPR119 (0.47) | S1PR1S1PR3LMNAHTTPDCD1 | |
| SCHEMBL21747444 | 0.84 | S1PR1 (0.50) | S1PR1S1PR3PDCD1CD274L3MBTL1 | |
| SCHEMBL21747468 | 0.83 | PDCD1 (0.47) | S1PR1S1PR3PDCD1CD274ALDH1A1 | |
| SCHEMBL21747451 | 0.81 | ALDH1A1 (0.49) | S1PR1S1PR3LMNAHTTALDH1A1 | |
| SCHEMBL21747469 | 0.80 | HSD17B10 (0.48) | S1PR1S1PR3LMNAHTTPDCD1 | |
| SCHEMBL21747490 | 0.79 | MAPT (0.52) | PDCD1CD274ALDH1A1MAPTMEN1 | |
| SCHEMBL21747446 | 0.76 | TP53 (0.49) | S1PR1S1PR3LMNAHTTALDH1A1 | |
| SCHEMBL6822046 | 0.75 | NPC1 (0.58) | ALDH1A1PKMMAPTMEN1KMT2A | |
| SCHEMBL21747464 | 0.75 | MAPT (0.55) | ALDH1A1MAPTMEN1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |