Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | C1R | P00736 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | KLK3 | P07288 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335514 | 0.82 | RAB9A (0.69) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL10730860 | 0.82 | HDAC6 (0.56) | MAPTKMT2AMEN1HDAC6RAB9A | |
| SCHEMBL3051786 | 0.81 | MMP2 (0.61) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL3043863 | 0.81 | NPC1 (0.61) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL21747490 | 0.81 | MAPT (0.52) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL2252128 | 0.80 | MAPT (0.68) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL12393101 | 0.78 | MMP2 (0.67) | MAPTKMT2AMEN1HDAC6RAB9A | |
| SCHEMBL15413444 | 0.78 | RAB9A (0.66) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL445014 | 0.77 | HDAC6 (0.74) | MAPTHDAC6RAB9AHDAC3HDAC1 | |
| SCHEMBL13767161 | 0.77 | RAB9A (0.67) | MAPTKMT2AMEN1HDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |