Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | C1R | P00736 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822046 | 0.83 | NPC1 (0.58) | MAPTKMT2AMEN1F2C1R | |
| Methane SCHEMBL6821779 | 0.82 | NPC1 (0.57) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL28335514 | 0.82 | RAB9A (0.69) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL3051786 | 0.81 | MMP2 (0.61) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL3043863 | 0.81 | NPC1 (0.61) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL21747464 | 0.81 | MAPT (0.55) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL2252128 | 0.80 | MAPT (0.68) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL21747473 | 0.80 | NPC1 (0.44) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL21747463 | 0.79 | S1PR1 (0.47) | MAPTKMT2AMEN1F2C1R | |
| SCHEMBL5641287 | 0.78 | TP53 (0.56) | MAPTKMT2AMEN1C1RPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |