Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CASP3 | P42574 | 2/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | C1R | P00736 | 1/20 | 0.55 |
| ▸ | CETP | P11597 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335514 | 0.85 | RAB9A (0.69) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3051786 | 0.84 | MMP2 (0.61) | NPC1RAB9AKDM4EALDH1A1CASP3 | |
| SCHEMBL3043855 | 0.84 | MAPT (0.61) | NPC1RAB9AKDM4EALDH1A1CASP3 | |
| SCHEMBL2252128 | 0.83 | MAPT (0.68) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21747490 | 0.81 | MAPT (0.52) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21747464 | 0.81 | MAPT (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4505279 | 0.78 | MAPT (0.58) | NPC1RAB9AKDM4EALDH1A1CASP3 | |
| SCHEMBL15413444 | 0.78 | RAB9A (0.66) | NPC1RAB9AKDM4EALDH1A1CASP3 | |
| SCHEMBL31451549 | 0.78 | KLK3 (0.58) | NPC1RAB9AKDM4EALDH1A1CASP3 | |
| SCHEMBL9867803 | 0.77 | MAPT (0.56) | NPC1RAB9AKDM4EALDH1A1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479282-B1 | Media including nitroreductase enzymatic substrates | BIOMERIEUX SA (FR) | 2018-03-28 | — | — | EP | disclosed |
| EP-2155893-B1 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | BIOMERIEUX SA (FR) | 2016-10-19 | — | — | EP | disclosed |
| EP-2479282-A1 | Media including nitroreductase enzymatic substrates | bioMérieux (FR) | 2012-07-25 | — | — | EP | disclosed |
| US-8211662-B2 | Nitroreductase enzymatic substrates | BIOMERIEUX (FR) | 2012-07-03 | — | — | US | disclosed |
| US-20100221764-A1 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | BIOMERIEUX (FR) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221764-A1 | NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES | CBR1, CBR3, XDH | NPC1 2202/4885RAB9A 4678/4885KDM4E 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.