SCHEMBL21748783

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4481228	0.82	USP30 (0.46)	KDM4E
	SCHEMBL21773364	0.82	USP30 (0.46)	KDM4E
	SCHEMBL16392349	0.71	ALDH1A1 (0.44)	ALDH1A1LMNAMAPTL3MBTL1KDM4E
	SCHEMBL4608020	0.68	ALDH1A1 (0.53)	ALDH1A1LMNAMAPTL3MBTL1KDM4E
	SCHEMBL4608025	0.68	ALDH1A1 (0.53)	ALDH1A1LMNAMAPTL3MBTL1KDM4E
	SCHEMBL3183827	0.67	RAB9A (0.67)	ALDH1A1LMNAMAPTL3MBTL1TSHR
	SCHEMBL1201854	0.67	ALDH1A1 (0.59)	ALDH1A1LMNAMAPTL3MBTL1KDM4E
	SCHEMBL3183837	0.67	RAB9A (0.67)	ALDH1A1LMNAMAPTL3MBTL1TSHR
	SCHEMBL15874872	0.67	ALDH1A1 (0.59)	ALDH1A1LMNAMAPTL3MBTL1KDM4E
	SCHEMBL1201856	0.67	ALDH1A1 (0.59)	ALDH1A1LMNAMAPTL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.