Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL21751207

Cc1ccc(C(CCCCCOB(O)O)(c2ccc(C)c(Cl)c2)c2ccc(C)c(Cl)c2)cc1Cl.N.N

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
RAB9A P51151 1/20 0.32
ESR1 P03372 2/20 0.32
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30
DRD3 P35462 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31598945 0.99 KIF11 (0.36) KIF11SMN1; SMN2NPC1CYP1A2CYP2C9
SCHEMBL1768493 0.99 KIF11 (0.36) KIF11SMN1; SMN2NPC1CYP1A2CYP2C9
SCHEMBL31697966 0.93 KIF11 (0.38) KIF11SMN1; SMN2NPC1CYP1A2CYP2C9
SCHEMBL30842595 0.87 THRB (0.37) SMN1; SMN2NPC1CYP1A2CYP2C9HPGD
SCHEMBL7661742 0.77 KIF11 (0.51) KIF11CYP2C9CYP2C19
Cetalkonium SCHEMBL25374375 0.77 DNM1 (0.47) KIF11SMN1; SMN2NPC1CYP1A2CYP2C9
Tetrabuthylammonium SCHEMBL123723 0.77 ESR1 (0.34) KIF11SMN1; SMN2NPC1CYP1A2CYP2C9
SCHEMBL25409958 0.76 HDAC3 (0.36) KIF11SMN1; SMN2
SCHEMBL809896 0.76 KIF11 (0.41) KIF11CYP2C9CYP2C19
SCHEMBL2230031 0.75 IGF1R (0.40) SMN1; SMN2NPC1CYP1A2CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11242360-B2 Process for the manufacturing of triaryl-organo borates COVESTRO DEUTSCHLAND AG (DE) 2022-02-08 US disclosed
US-20200062786-A1 PROCESS FOR THE MANUFACTURING OF TRIARYL-ORGANO BORATES COVESTRO DEUTSCHLAND AG (DE) 2020-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200062786-A1 PROCESS FOR THE MANUFACTURING OF TRIARYL-ORGANO BORATES PARG, BRS3, BLVRB KIF11 2761/4885SMN1; SMN2 4700/4885NPC1 3844/4885
US-11242360-B2 Process for the manufacturing of triaryl-organo borates PARG, BRS3, BLVRB KIF11 2761/4885SMN1; SMN2 4700/4885NPC1 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.