Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751681 | 0.74 | CDK8 (0.36) | ROCK2 | |
| SCHEMBL23165280 | 0.65 | DGAT1 (0.40) | ABCB1MAPTALDH1A1L3MBTL1DGAT1 | |
| SCHEMBL21751713 | 0.62 | CDK8 (0.33) | — | |
| SCHEMBL9611293 | 0.61 | ALDH1A1 (0.47) | ABCB1ATMMAPTALDH1A1TDP1 | |
| SCHEMBL23908158 | 0.61 | RIPK1 (0.30) | — | |
| SCHEMBL21751683 | 0.60 | HSP90AA1 (0.30) | — | |
| SCHEMBL21751780 | 0.60 | PDE3B (0.33) | — | |
| SCHEMBL24005756 | 0.60 | CDK8 (0.47) | ROCK2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL23836500 | 0.60 | ABCB1 (0.45) | ABCB1MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL857388 | 0.59 | NAMPT (0.52) | ROCK2MAPTALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041406-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2020-02-27 | — | — | WO | disclosed |