Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.67 |
| ▸ | FAAH | O00519 | 1/20 | 0.67 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.67 |
| ▸ | MGLL | Q99685 | 1/20 | 0.67 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | PPARD | Q03181 | 2/20 | 0.60 |
| ▸ | PPARA | Q07869 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21964138 | 0.90 | FAAH (0.65) | MAPTBLMFAAHKDM4EPPARG | |
| SCHEMBL22525234 | 0.85 | ALDH1A1 (0.73) | ALDH1A1MAPTBLMPLA2G4AFAAH | |
| SCHEMBL20968796 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAPTBLMPLA2G4AFAAH | |
| SCHEMBL3477050 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTBLMPLA2G4AFAAH | |
| Arachidonyl Trifluoromethylketone SCHEMBL9880640 | 0.80 | FAAH (1.00) | ALDH1A1MAPTBLMPLA2G4AFAAH | |
| Arachidonyl Trifluoromethylketone SCHEMBL30426991 | 0.80 | FAAH (1.00) | ALDH1A1MAPTBLMPLA2G4AFAAH | |
| SCHEMBL20968838 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTBLMPLA2G4AFAAH | |
| Arachidonamide SCHEMBL6667074 | 0.79 | CNR1 (1.00) | ALDH1A1MAPTBLMFAAHCNR1 | |
| Arachidonamide SCHEMBL542347 | 0.79 | CNR1 (1.00) | ALDH1A1MAPTBLMFAAHCNR1 | |
| Arachidonamide SCHEMBL542346 | 0.79 | CNR1 (1.00) | ALDH1A1MAPTBLMFAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3840769-A1 | CYCLOSPORINE COMPOSITIONS AND METHODS OF USE | Bacainn Biotherapeutics, Ltd. (KY) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020041378-A1 | CYCLOSPORINE COMPOSITIONS AND METHODS OF USE | BACAINN THERAPEUTICS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |