Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | FAAH | O00519 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.68 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.68 |
| ▸ | MGLL | Q99685 | 1/20 | 0.68 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 5/20 | 0.66 |
| ▸ | F7 | P08709 | 4/20 | 0.66 |
| ▸ | F3 | P13726 | 4/20 | 0.66 |
| ▸ | PPARD | Q03181 | 4/20 | 0.66 |
| ▸ | PPARA | Q07869 | 4/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.66 |
| ▸ | CASP6 | P55212 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20968838 | 0.98 | ALDH1A1 (0.67) | ALDH1A1FAAHMAPTBLMPLA2G4B | |
| SCHEMBL22525234 | 0.96 | ALDH1A1 (0.73) | ALDH1A1FAAHMAPTBLMPLA2G4B | |
| SCHEMBL22525183 | 0.93 | FAAH (0.71) | FAAHMAPTBLMPPARGF7 | |
| SCHEMBL25834781 | 0.93 | FAAH (0.71) | FAAHMAPTBLMPPARGF7 | |
| SCHEMBL25835999 | 0.93 | FAAH (0.71) | FAAHMAPTBLMPPARGF7 | |
| SCHEMBL23772133 | 0.93 | FAAH (0.71) | FAAHMAPTBLMPPARGF7 | |
| SCHEMBL22525273 | 0.93 | FAAH (0.71) | FAAHMAPTBLMPPARGF7 | |
| SCHEMBL114309 | 0.93 | FAAH (0.71) | FAAHMAPTBLMPPARGF7 | |
| SCHEMBL25836005 | 0.93 | FAAH (0.71) | FAAHMAPTBLMPPARGF7 | |
| SCHEMBL22525182 | 0.91 | ALDH1A1 (0.57) | ALDH1A1FAAHMAPTBLMPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295617-A1 | METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS | WAVE LIFE SCIENCES LTD. (SG) | 2023-09-21 | — | — | US | disclosed |
| US-20230295617-A1 | METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS | WAVE LIFE SCIENCES LTD. (SG) | 2023-09-21 | — | — | US | disclosed |
| US-20190249173-A1 | METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS | WAVE LIFE SCIENCES LTD. (SG) | 2019-08-15 | — | — | US | disclosed |
| US-20190127733-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127733-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | RBM17, HNRNPA2B1, HNRNPA1 | ALDH1A1 3613/4885FAAH 4643/4885MAPT 1951/4885 |
| US-20230295617-A1 | METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS | ELOVL6, ELOVL5, ELOVL1 | ALDH1A1 2846/4885FAAH 162/4885MAPT 3184/4885 |
| US-20190249173-A1 | METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS | ELOVL6, ELOVL5, ELOVL1 | ALDH1A1 2811/4885FAAH 163/4885MAPT 2954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.