Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409861 | 0.87 | TRPA1 (0.41) | TRPA1ATMALDH1A1HTR1BMAPT | |
| SCHEMBL447683 | 0.79 | TRPA1 (0.41) | TRPA1ATMALDH1A1HTR1BMAPT | |
| SCHEMBL18315768 | 0.77 | TRPA1 (0.39) | TRPA1ATMALDH1A1HTR1BMAPT | |
| SCHEMBL2175294 | 0.76 | TRPA1 (0.48) | TRPA1ATMALDH1A1MAPTCYP1A2 | |
| SCHEMBL1894227 | 0.75 | TRPA1 (0.38) | TRPA1ATMALDH1A1HTR1BMAPT | |
| SCHEMBL5954109 | 0.74 | TRPA1 (0.39) | TRPA1ATMALDH1A1MAPTCYP1A2 | |
| SCHEMBL17865480 | 0.73 | TRPA1 (0.37) | TRPA1ATMALDH1A1HTR1BMAPT | |
| SCHEMBL707653 | 0.73 | PTPN1 (0.41) | TRPA1ATMALDH1A1MAPTCYP1A2 | |
| SCHEMBL11278838 | 0.73 | HTR1B (0.35) | TRPA1ATMHTR1BMAPTLMNA | |
| SCHEMBL11799546 | 0.73 | TRPA1 (0.38) | TRPA1ATMALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125834-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | Wacker Chemie AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| EP-2125833-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | Wacker Chemie AG (DE) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008090013-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008090012-A1 | METHOD FOR THE PRODUCTION OF POLYMERISABLE SILICONES | WACKER CHEMIE AG (DE) | 2008-07-31 | — | — | WO | disclosed |