Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092555 | 0.86 | LDHA (0.33) | MAPK1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21753502 | 0.84 | ALDH1A1 (0.35) | SMN1; SMN2USP2RAB9AALDH1A1KDM4E | |
| SCHEMBL21753524 | 0.84 | ALDH1A1 (0.38) | MAPK1SMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL28854513 | 0.84 | CA12 (0.38) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL21891257 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL21753516 | 0.77 | TSHR (0.40) | MAPK1SMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL860052 | 0.74 | PARP1 (0.44) | ALDH1A1CCNA2CDK2CCNA1NOTUM | |
| SCHEMBL1274356 | 0.67 | LDHA (0.36) | LDHA | |
| SCHEMBL29217620 | 0.67 | LDHA (0.34) | LDHA | |
| SCHEMBL28200009 | 0.64 | LDHA (0.35) | CCNA2CDK2CCNA1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038460-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | 南京药捷安康生物科技有限公司 | 2020-02-27 | — | — | WO | disclosed |