Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753502 | 0.82 | ALDH1A1 (0.35) | NOTUMALDH1A1CCNA2CDK2CCNA1 | |
| SCHEMBL21753524 | 0.82 | ALDH1A1 (0.38) | PARP1RIPK2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL22092555 | 0.75 | LDHA (0.33) | HSP90AA1MGLLALDH1A1PARP10LMNA | |
| SCHEMBL21753518 | 0.74 | MAPK1 (0.35) | NOTUMALDH1A1CCNA2CDK2CCNA1 | |
| SCHEMBL21891257 | 0.73 | ALDH1A1 (0.45) | PARP1L3MBTL1ALDH1A1CCNA2CDK2 | |
| SCHEMBL28854513 | 0.70 | CA12 (0.38) | NOTUMALDH1A1CCNA2CDK2CCNA1 | |
| SCHEMBL21753516 | 0.70 | TSHR (0.40) | NOTUMMGLLALDH1A1LMNA | |
| SCHEMBL1274356 | 0.67 | LDHA (0.36) | PARP1 | |
| SCHEMBL20829870 | 0.63 | LDHA (0.34) | — | |
| SCHEMBL677632 | 0.63 | LDHA (0.37) | PARP1PARP10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432763-A1 | 1,4 DIHYDROPYRIDINE DERIVATIVES AND THEIR USES | Université de Lille 2 Droit et Santé (FR) | 2012-03-28 | — | — | EP | claimed |