Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753551 | 1.00 | CHRM1 (0.36) | CHRM1MEN1KMT2AMAPTCASP3 | |
| SCHEMBL21753545 | 0.92 | L3MBTL1 (0.36) | MEN1KMT2AMAPTL3MBTL1TSHR | |
| SCHEMBL21753508 | 0.87 | RAB9A (0.37) | EPHX2ALDH1A1FAAHCTSLNPC1 | |
| SCHEMBL21753506 | 0.87 | RAB9A (0.37) | EPHX2ALDH1A1FAAHCTSLNPC1 | |
| SCHEMBL21753556 | 0.79 | NPC1 (0.38) | MEN1KMT2AMAPTEPHX2ALDH1A1 | |
| SCHEMBL21753573 | 0.74 | RAB9A (0.41) | MEN1KMT2AMAPTEPHX2PPARG | |
| SCHEMBL16109883 | 0.73 | MAPT (0.51) | MEN1KMT2AMAPTCASP3TRPV1 | |
| SCHEMBL16109884 | 0.73 | MAPT (0.51) | MEN1KMT2AMAPTCASP3TRPV1 | |
| SCHEMBL21769290 | 0.72 | CHRM1 (0.38) | CHRM1MEN1KMT2AMAPTCASP3 | |
| SCHEMBL30106507 | 0.72 | CHRM1 (0.38) | CHRM1MEN1KMT2AMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038460-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | 南京药捷安康生物科技有限公司 | 2020-02-27 | — | — | WO | disclosed |