Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753508 | 0.89 | RAB9A (0.37) | NPC1RAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL21753506 | 0.89 | RAB9A (0.37) | NPC1RAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL21753545 | 0.88 | L3MBTL1 (0.36) | NPC1RAB9ASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL21753550 | 0.79 | CHRM1 (0.36) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL21753551 | 0.79 | CHRM1 (0.36) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL23832199 | 0.70 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL12560996 | 0.66 | CES2 (0.61) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL2830742 | 0.66 | CES2 (0.61) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL2830740 | 0.66 | CES2 (0.61) | NPC1RAB9ASMN1; SMN2HPGDPOLB | |
| SCHEMBL1939156 | 0.66 | CES2 (0.61) | NPC1RAB9ASMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038460-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | 南京药捷安康生物科技有限公司 | 2020-02-27 | — | — | WO | disclosed |